Atlas des hypothèses BERM

Explorez les voies multiniveaux proposées par BERM et leurs étiquettes de preuve, des canaux EMF aux résultats démographiques et écologiques.

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Every identified channel in one shared graph. Select a subatlas to examine a smaller part; shared nodes connect the views.

Pharmacological experiments across subatlases

Shared nodes connect the subatlases. Each node has one description across all views. Les descriptions des voies sont disponibles en anglais et en finnois.

How is the evidence in this view organized?

72 / 254 channels have claim bindings; claims in 70 channels have study relations. This view contains 120 distinct claims and 352 study–claim relations.

These counts describe curation. A study may relate to several claims; the counts do not measure independent experiments or calibrated effects. Open a channel to inspect the precise claim and its scope.

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254 / 254 channels shown · 626 connections

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Connection types

Conditional model link
Modifies the response
Relative ecological effect
Measurement / inference input
Conditional L2 response · calibration open
Derivation under stated premises
Feedback over time
Observation / association

Premises & bridges (5)

Conditional metric-to-observable response operator — [CONDITIONAL · L2] Under minimal matter–metric coupling and response theory, BERM specifies δ⟨O_i⟩ = ∫Ξ_i^{μν}δg_{μν} plus higher-order response. Its gauge, physical scale, observer, tissue kernel and endpoint calibration remain open. Downstream component evidence cannot determine these by itself.En savoir plus
Lindgren 2025 metric perturbation and quadratic mixing drive — Under g = η + κA⊗A, δg = κ(Ā⊗a + a⊗Ā + a⊗a) preserves cross terms and quadratic waveform mixing. The normalized rank-one coordinate is geometric; a biological response additionally requires BERM's conditional matter-coupling and response premises, with gauge, physical scale and tissue calibration stated separately.En savoir plus
Lindgren 2025 premise — [L0] The selected 2025 ansatz is gμν = ημν + κAμAν (κ = 1 in the paper normalization). It is not the singular 2021 ansatz g = A⊗A. The variational branch, Weyl connection and sourced dynamics must be stated separately.En savoir plus
Tensor perturbation δg — [L1] For A = Abio + aext, δgμν = κ(Abio,μ aext,ν + aext,μ Abio,ν + aext,μ aext,ν). This is a tensor identity conditional on the decomposition. A scalar response requires an explicit contraction or measurement operator.En savoir plus
Metric domain and geometric χ — [L1] det(g) = det(η)(1 + κA²); g⁻¹ exists only for 1 + κA² ≠ 0. The abstract dimensionless χgeo(x) = x/√(1+x²) has a stated mathematical domain. Identifying x with a spatial projection, local field or biology is an additional L2 proposition.En savoir plus

Physical inputs (12)

STATIC (0 Hz) — Triboelectric material–organism interfaces can create local static fields and gradients. Biological interpretation requires measured charge, voltage, humidity and grounding; historical textile results do not establish a universal reproductive dose.En savoir plus
ELF (< 1 kHz) — BERM treats membrane-potential perturbation by 50/60 Hz fields and harmonics as a candidate route. Its formal L2 response has a defined operator shape, but the relevant field-to-membrane tissue kernel must be calibrated for the system and exposure.En savoir plus
IF (1k–1M Hz) — Switch-mode power supply 20–300 kHz fields penetrate into the cell interior (T(f) high-pass). IFO-VGIC linear response, threshold 10⁻⁵ V/m. Regulatory gap: ELF limits < 300 Hz, RF limits > 100 kHz. IF falls between. IJRB 2022: 'studies have NOT been conducted.' Exponential growth 2009–2019 (EU incandescent lamp ban). Cyb5b (Kim 2026 Cell i): IF frequency produces Ca²⁺ oscillations that control gene expression.En savoir plus
RF (> 1 MHz) — BERM treats the independently studied radical-pair/cryptochrome response as a candidate RF-sensitive route. No RPM or cryptochrome coupling has been derived from Lindgren geometry. Deprez et al. 2025 measured 5G spectra in four European countries; those observations can inform a future calibrated input layer.En savoir plus
Electrification boundary — Historical electrification is a timing and source-development context. A universal biological threshold cannot be inferred from national infrastructure or a scalar proxy.En savoir plus
Solar-geomagnetic — The Sun's 11-year cycle modulates Earth's geomagnetic environment: solar maximum → CMEs and coronal hole streams → geomagnetic disturbances. These perturb CRY's radical pair mechanism (χ_B channel) and suppress pineal melatonin production. The effect is latitude-dependent: strongest at the auroral oval (geomag lat > 60°), weakest in the tropics, and anomalous in the SAMA region (Southern Brazil). The cycle has operated for 290 million years (dendrochronology) and is documented in human birth rate data from 7 countries (Randall 1990/1993) and pre-industrial Norway (Skjærvø 2015: N=8662, 1676-1878).
Local physical state — The proposed physical input carries electric and magnetic fields, vector orientation, phase, spectrum, timing and local boundary conditions. FieldState observations estimate these variables; national technology timing cannot replace a local measurement.En savoir plus
Optical light and timing — Wavelength, photon sequence, retinal transmission and circadian timing form an optical input distinct from the electric and magnetic fields of lighting electronics. Light and EMF must be measured separately.En savoir plus
Thermal and tissue-temperature route — Temperature is a separate local transfer and control variable; sperm function and CatSper gating can respond to tissue temperature. Physical structure or a source/measurement context, not an identified biological dose coefficient. Any geometry-to-biology interpretation uses the conditional L2 operator under additional matter-coupling and response premises; gauge, physical scale and tissue calibration remain open.En savoir plus
Natural ELF reference and masking — The site proposes natural ELF timing cues and their masking by urban noise as a distinct space-weather/circadian hypothesis. Physical structure or a source/measurement context, not an identified biological dose coefficient. Any geometry-to-biology interpretation uses the conditional L2 operator under additional matter-coupling and response premises; gauge, physical scale and tissue calibration remain open.En savoir plus
Pc1 geomagnetic pulsations — Natural ULF/Pc1 time structure is associated with cardiac and autonomic measurements in the site’s heliobiology literature. Physical structure or a source/measurement context, not an identified biological dose coefficient. Any geometry-to-biology interpretation uses the conditional L2 operator under additional matter-coupling and response premises; gauge, physical scale and tissue calibration remain open.En savoir plus
Space weather–grid interaction — Geomagnetically induced currents can change transformer operating states and grid harmonics; the indoor exposure and health transfer require measurements. Physical structure or a source/measurement context, not an identified biological dose coefficient. Any geometry-to-biology interpretation uses the conditional L2 operator under additional matter-coupling and response premises; gauge, physical scale and tissue calibration remain open.En savoir plus

Measurement & evidence (7)

Kaiser Permanente series — An epidemiological series is an observation, not a biological intermediate. Personal magnetic-field records and outcome associations require frequency-resolved exposure and confounder control; they do not isolate an IF mechanism.En savoir plus
National technology-timing proxy (legacy v17 comparison) — Legacy national technology timing is a comparison input, not a measured local physical dose or a calibrated forecast.En savoir plus
FieldState vector/phase observation and organ-transfer estimate — FieldState records vector, orientation, phase and organ-transfer estimates with measurement uncertainty. These observations constrain a physical-state estimate; they do not cause the biological response.En savoir plus
Measured envelope/beat spectral overlap — Measured spectral power, modulation envelopes, beats and timing can constrain a receiver-window overlap. An independently specified transfer operator and calibration are required.En savoir plus
Static triboelectric material–skin / organism-interface state — Measure charge, voltage, local electric field, gradients, material, humidity and grounding at the organism interface. Textile composition alone is not a dose.En savoir plus
Measured low-frequency electric-field waveform and polarity state — Record the electric-field waveform, AC/DC polarity, orientation, duration and local geometry independently of magnetic-field measurements.En savoir plus
Population comparison and controls — Population comparisons such as Amish cohorts are observation and confounding-control contexts. They do not isolate an electromagnetic mechanism: lifestyle, genetics, selection, measurement and outcomes must be matched.En savoir plus

Response modifiers (43)

1. Conditional L2 response — Lindgren's 2025 ansatz g_μν = η_μν + κA_μA_ν is the theory premise. BERM derives the exact δg and, conditional on minimal matter coupling and response theory, δ⟨O_i⟩ = ∫Ξ_i^{μν}δg_{μν}+…. Gauge, scale, tissue kernel Ξ_i and endpoint calibration remain open. Metric-volume linearization/geodesic deviation yields a signed directional response and the algebraic χ_geo(q)=q/√(1+q²) formula at L1; choosing q=|Ā| through a dimensionless, collinear Lorentz-to-Euclidean spatial/scalar projection is an L2 reduction. A raw V/m value, proxy, V_m or membrane coordinate cannot be inserted directly; the identification mapping one to q=N(z) remains open at L0→L2, and downstream mechanisms are imported L3 components.En savoir plus
2. Ion channel network — VGCC, Nav, K-ATP, CatSper — all electrically modulable. S4 voltage sensor responds via IFO mechanism at 10⁻⁵ V/m. Non-ionotropic signaling (Trus & Atlas 2024 i) lowers the threshold.En savoir plus
3. DC control system — Perineural semiconductor network that controls tissue growth, healing, and regeneration via DC currents. Disruption → depolarization → loss of growth control.En savoir plus
4. Bioelectric code — Vmem gradients control cell differentiation, morphogenesis, and cancer formation. Depolarization = 'cancer phenotype' (Levin).En savoir plus
5. Circadian clock — Cryptochrome RPM mechanism + pineal gland melatonin synthesis. EMF disrupts both: RPM directly, melatonin via SCN.En savoir plus
6. Vagus axis — Vagus nerve cholinergic anti-inflammatory reflex. VNS activation → inflammation decreases. Chronic EMF disruption → reflex weakens → chronic inflammation.En savoir plus
7. Cell division — IF field disrupts mitotic spindle assembly. Geometric field amplification at the cleavage furrow G ≈ 25×. f_opt = K/d_cell (K ≈ 3.7 Hz·m).En savoir plus
8. Mitochondrial — Cytochrome c oxidase (CCO) absorbs red/NIR light → ATP↑, ROS modulation. Non-thermal electromagnetic interaction with the chromophore.En savoir plus
9. Cyb5b signalling mediator — A genome-wide CRISPR screen identified Cyb5b as an essential mediator and candidate sensor in an engineered EMF-responsive gene switch. The laboratory protocol combines 60 Hz burst repetition with 4 kHz pulses within each active burst; rhythmic Ca²⁺ oscillations precede promoter activation. The necessity of Cyb5b does not by itself locate the first physical interaction.En savoir plus
FAD / riboflavin (B2) — Flavin availability, binding and turnover can modify cryptochrome state in subtype-specific systems. Hirano 2017 i links FAD to CRY stability; Iversen 2025 i tests CRY2/RFK/FAD–TRPC1 myogenesis under a defined pulsed magnetic protocol. The model carries cofactor and light-history state into the receiver response. These components do not determine the sign of a human B2 supplement effect on environmental RF, melatonin or fertility.
Membrane lipid order — European robin Cry4a associates with model lipid bilayers with a measurable orientation and membrane-state dependence (Majewska et al. 2025 i). This supplies a receiver-orientation variable for an explicitly proposed magnetic response model. The experiment did not apply a field or measure a reproductive endpoint. Dietary omega-3/7 → tissue lipid state → orientation → magnetic response remains a sequence of separate transfer functions; mammalian CRY1 is a different subtype.
AMPK fasting dynamics — AMPK phosphorylates CRY1 at Ser71 → FBXL3 ubiquitination → degradation (Lamia et al. 2009 i, Science). Fasting paradox: AMPK degrades old CRY, but simultaneously increases FAD pool via β-oxidation, so newly synthesized CRY is better FAD-loaded. Net effect depends on CRY turnover rate vs. FAD availability — resolution is L*-level hypothesis.
Molecular (Spin & Chromophore) — Imported response-modifying layer: CRY1, CRY2, FAD, FADH•, tryptophan chain, sequential two-photon step, RFK. State variables: Flavin redox state, binding occupancy and the ordered light history. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Ion Channel (Gating Dynamics) — Imported response-modifying layer: Cav1 (L-type), Cav3 (T-type), TRPC1, CatSper, K_ATP, KCNJ15/Kir4.2. State variables: Vm vs channel threshold; store load and resting potential at fixed channel expression. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Mitochondrial (ΔΨm Ca²⁺→ROS Converter) — Imported response-modifying layer: VDAC (outer), MCU (inner, Ca²⁺ uniporter), ETC complexes I–IV, respiratory reserve, ATP output, mitochondrial number. State variables: ΔΨm ≈ −180 mV (>2× plasma membrane), read as a functional state with respiratory reserve, ATP output and mitochondrial number. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Membrane & Biological Barriers — Imported response-modifying layer: Occludin, claudin, ZO-1; ω-3/7 lipids; BBB, BTB, BRB, placenta; TRPC1 complexes, cell-derived vesicles. State variables: Membrane composition, protein complexes and their localisation, plus TJ integrity. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Redox Defense (Buffer Capacity) — Imported response-modifying layer: GSH/GSSG ratio, glutathione reductase (GR, requires FAD), SOD1/2, catalase, Nrf2 pathway, autophagic flux, ATG5/ATG7, challenge tolerance. State variables: Repair capacity measured separately from damage load: glutathione reserve, SOD, catalase, autophagic flux. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Cell Type (χ_tissue Expression Profile) — Imported response-modifying layer: Leydig (Cav3), gonadotroph (Cav3), β-cell (Cav1+3), cardiomyocyte (Cav1.2), KCNJ15 + polyamines, PI3Kγ, PTEN. State variables: Cell-specific channel expression, plus polarity and the spatial PIP₃ distribution. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Organ (Composite χ_organ Profile) — Imported response-modifying layer: Eye, testes, pituitary, adrenal, pancreas, hippocampus, heart, thyroid; cell density, secreted mediators, recipient-cell state, immune cells. State variables: Combined cell types + vascularization + barrier status + dielectric properties + the local tissue environment. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Autonomic Nervous System (System-Wide Modulator) — Imported response-modifying layer: SA node (Cav3 pacemaking), vagus nerve, cholinergic anti-inflammatory pathway, baroreflexes. State variables: HRV, vagal tone, sympathetic/parasympathetic balance. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Endocrine Axes (HPG, HPA, HPT) — Imported response-modifying layer: HPG (FSH/LH), HPA (ACTH/cortisol), HPT (TSH/T3/T4), prolactin. State variables: Pituitary T-type channels → all hormone secretion. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Circadian Timing — Imported response-modifying layer: SCN, pineal, CRY1/2, peripheral clocks. State variables: Light spectrum, CRY photocycle, melatonin. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Individual Variation — Imported response-modifying layer: CACNA1C genotype with a named sleep-spindle endpoint, CACNA1G T-type SNPs, OCA2, LCT, B2 status, declared cell history (passage, differentiation, prior exposures). State variables: Measured exposure-by-genotype interactions, nutrition (B2, ω-3), sex, age. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Population & Environment — Imported response-modifying layer: χ_env, COVID-WFH test, population χ profiles. State variables: Electrification, urbanization, dairy consumption patterns. This biological response modifier is not the restricted geometric χ_geo coefficient.En savoir plus
Receiver state and cell history — Receptor readiness, repair capacity and residual damage are separate measured states. Prior exposure, culture history and differentiation can change the next response without the same underlying mechanism.En savoir plus
Autophagy and repair memory — ATG5/ATG7-dependent repair can reduce residual oxidative DNA damage after a later challenge. Reduced incremental damage can therefore reflect adaptation; it does not by itself identify geometric saturation or receptor weakening.En savoir plus
Membrane machinery and transfer — Receptor competence depends on channel density, lipid order, complex integrity and location. Prepared TRPC1-containing vesicles partly restored responses in recipient cells; native transfer within tissue is a separate hypothesis.En savoir plus
CRY subtype and light history — CRY identity, flavin occupancy/redox state and ordered photon history determine the candidate receiver state. Equal summed light dose can leave different molecular states; magnetic modulation of the human CRY1 photochemical transition remains a separate test.En savoir plus
State-dependent response window — The candidate spectral operator integrates a defined biological driver through W(f; cell state, B0). The measured receiver state, rather than a technology-generation label, sets the window; parameters require independent registration.En savoir plus
Genetic, anatomical and lifetime modifiers — CACNA1C and antioxidant variation, tissue geometry and cumulative allostatic history define separate susceptibility dimensions. The current individual calculator is diagnostic and its multipliers are not calibrated population coefficients.En savoir plus
Developmental timing and exposure history — The legacy cohort route weights lifetime inputs by age and retention. Developmental exposure and current exposure remain separate histories; the national technology proxy is a timing scenario, not measured local dose.En savoir plus
Driver × receiver window — The dual-kernel candidate separates background-dependent sensitivity from a measured time-varying driver. Integrate its spectrum against a predeclared receiver window; equal broadband power does not imply equal overlap. Neither kernel is a measured reproductive coefficient.En savoir plus
Buildings, grounding and local exposure — Building materials, source placement, grounding, distance and time indoors can modify local field structure and recovery opportunities. Physical structure or a source/measurement context, not an identified biological dose coefficient. Any geometry-to-biology interpretation uses the conditional L2 operator under additional matter-coupling and response premises; gauge, physical scale and tissue calibration remain open.En savoir plus
Vitamin D and channel expression — VDR-dependent regulation of CACNA1C/CACNA1D is an imported candidate modifier of calcium-channel expression. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Magnesium and calcium buffering — Magnesium availability can modify calcium handling and excitability; the site includes it among natural response modifiers. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Trace lithium, GSK-3β and clocks — The site combines lithium-associated GSK-3β, BDNF and clock mechanisms with ecological drinking-water associations; these remain different evidence types. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Caffeine and adenosine receptors — Adenosine A1/A2A antagonism provides a separate modifier of calcium signalling, alertness and dopamine-related responses. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Metals and calcium-route interactions — Cd, Pb, Hg, Al and fluoride have distinct entry, signalling or mineralisation hypotheses; they cannot be pooled as one EMF dose. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Chemical endocrine co-exposures — Chemical endocrine disruptors provide competing and interacting hypotheses for developmental steroid, immune and reproductive endpoints. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Channel-expression priming — The website proposes that sustained ELF exposure can alter channel expression and hence the response to a later RF/IF input. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Exposure gaps and recovery — Pulse spacing, overnight exposure, shift work and prior state determine the proposed accumulation-versus-recovery balance. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Receptor and channel interventions — The site uses calcium-channel drugs, GABA/HCN agents and serotonergic plasticity interventions to bound particular biological links. Rescue or drug efficacy does not identify the environmental cause. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Light-dependent active drug fraction — Light rapidly reversed nifedipine and nisoldipine channel blockade in Purkinje fibres, especially at 320–450 nm. The compared nicardipine, nitrendipine and D600 blocks did not behave the same way in that protocol. Illumination may change active drug availability separately from the biological receiver state.En savoir plus

Cell mechanisms (62)

Vmem/VGCC → Ca2+ → mitochondrial ROS — Imported Vmem/VGCC–Ca²⁺–mitochondrial/redox biology. Receptor state and baseline calcium matter; ROS has a functional window. RyR release and SERCA reuptake are coupled parts of an ER–cytosol–mitochondrial cycle, not independent exposure pathways. The L2 operator form is conditional; gauge, scale and observable-specific calibration remain open.En savoir plus
T-type Cav3 bifurcation — Cav3 T-type channels operate near resting potential, with a window current. Schwan-equation membrane estimates and the reported Ca²⁺ pathways make Cav3 a candidate BERM tissue kernel. The formal L2 operator shape is conditional; Cav3 transfer, sign, lag and calibration are not derived by geometry. In Leydig cells: Ca²⁺ → StAR → testosterone. In spermatogenesis: Ca²⁺ → development timing (Ma 2026i).En savoir plus
GPCR-adenosine → cAMP — PEMF mechanism: adenosine A2A receptor activation → cAMP cascade → anti-inflammatory response.En savoir plus
Nav → neuroplasticity — Sodium channel modulation → cortical plasticity. The basic mechanism of rTMS and tDCS.En savoir plus
Radical-pair/cryptochrome → clock/redox state — Imported radical-pair, cryptochrome, clock and redox mechanisms must be specified by cryptochrome subtype, species, flavin state and light history. Photochemical response does not by itself establish magnetic modulation. A universal coefficient for all eukaryotes is not assumed; the L2 operator is conditional, with gauge, scale and tissue calibration open.En savoir plus
CRY2 → TRPC1 Ca²⁺ — CRY2-dependent, light-dependent, FAD-dependent calcium entry through TRPC1 (a TRP channel, NOT a VGCC). CRY2 physically interacts with TRPC1; the complex co-translocates to the nucleus after EMF/PEMF exposure. Pharmacologically distinct from pathway A: not blocked by nifedipine/verapamil. Demonstrated in myoblasts (Iversen et al. 2025 i, Cells).En savoir plus
Vagal anti-inflamm. — Vagus nerve cholinergic reflex: acetylcholine → α7nAChR → NF-κB inhibition → inflammation control.En savoir plus
Mitotic spindle → aneuploidy — IF field disrupts tubulin polymerization and spindle orientation → incorrect chromosome segregation.En savoir plus
Ion forced-oscillation candidate — A declared ion-oscillation model proposes a linear response under specified forcing, damping, charge/mass and boundary assumptions. Its model-specific threshold is not a universal measured biological dose; the receiving operator and tissue transfer require calibration.En savoir plus
DEP quadratic (>100 V/m) — Dielectrophoresis: quadratic force on polarized particles in an inhomogeneous field. TTFields intensity.En savoir plus
Cyb5b → Ca²⁺ oscillations — CRISPR-screen-identified Cyb5b functions as an EMF sensor on the outer mitochondrial membrane. Produces rhythmic Ca²⁺ oscillations that activate gene promoters. Third transduction pathway alongside IFO and RPM. 4 kHz (IF range) was used in the gene switch demonstration — links the IF channel directly to gene expression control cascade.En savoir plus
VGCC genotype × sensitivity — Genotype-by-exposure interactions must be tied to the measured endpoint and protocol, including the bounded EEG component findings. They motivate stratified tests, not a universal individual or population susceptibility coefficient.En savoir plus
β-cell K-ATP → insulin — US Patent 4,850,959 (1989)i: resonance-frequency EMF controls pancreatic β-cell insulin secretion via Ca²⁺ channels. Resonance → Ca²⁺ influx → insulin↑. Non-resonance → Ca²⁺ efflux → insulin↓.En savoir plus
Window effect — Biological effect is non-linear: Ca²⁺ efflux from brain tissue occurs at specific intensity windows (0.1–1.0 mW/cm²) but NOT at higher or lower levels. Explains why ICNIRP's linear SAR model does not detect effects and why replication studies may fail.En savoir plus
Ionic treatment hierarchy — All mood disorder treatments converge on Ca²⁺ homeostasis: SSRI (indirect, NNT 7) < TMS/tDCS (electromagnetic, NNT 5) < lithium (ionic, Li⁺→VGSC) < psychedelics (ionic reset, 5-HT2A→Cav1.2/CACNA1C, NNT 3). Efficacy follows the degree of ionic targeting.En savoir plus
Dermal bioelectric system — Epidermis maintains transepithelial potential (TEP, 10–60 mV) via Na⁺/K⁺-ATPase. Dermal collagen is piezoelectric (7–8 pC/N) and converts mechanical force to voltage that opens VGCC channels. PIEZO1/TRPV4/VGCC converge on Ca²⁺ response. EMF disrupts all three systems simultaneously.En savoir plus
LED IF-EMF confound — All LED light sources contain a switch-mode power supply (20–300 kHz IF-EMF). Retinal Cav1.4 channels are VGCC-type and IF-EMF targets. In blue light studies, incandescent vs. LED comparison is confounded by IF-EMF. A2E photosensitization is real, but IF-EMF may amplify it synergistically. Night mode removes blue light but NOT IF-EMF. Duraccio 2019i: blue light filter glasses did NOT improve sleep — suggesting IF role.En savoir plus
Hospital EMF — Post-hospital syndrome (Krumholz NEJM 2013 i): risk for all diagnoses 30 days after discharge. Hospitals are the highest-EMF environment: 24/7 LED (IF), Wi-Fi (RF), monitors (IF+ELF), electric beds (ELF). ICU: 40 µT near devices. Elderly 95% of time in bed. BERM: simultaneous modulome activation in impaired ion channel homeostasis.En savoir plus
Amyloid-calcium feedback — EMF → VGCC → Ca²⁺ ↑ → BACE1 → Aβ oligomers. In the presence of Ca²⁺, Aβ forms toxic oligomers (Bhatt PMC3065491 i). Oligomers form membrane Ca²⁺ pores → positive feedback loop. Presenilin convergence: PSEN1/2 mutations (genetic) and EMF-VGCC (environmental) converge on the same Ca²⁺ pathway. Arendash paradox: controlled EMF protects (918 MHz, MemorEM/TEMT) — dose/frequency/context determine outcome.En savoir plus
ADHD calibration error — Prenatal EMF → fetal VGCC activation → Ca²⁺ disruption in critical developmental window → ion channel (HCN, VGCC, KCNQ) calibration error in PFC pyramidal neurons → signal-to-noise ratio deficit → ADHD phenotype. CACNA1C variants associate with ADHD, ASD, bipolar disorder in GWAS. Timothy syndrome (CACNA1C GoF) → autism = genetic extreme example. Guanfacine (FDA/EMA ADHD) works DIRECTLY on ion channels: α2A → cAMP↓ → HCN closes → Vm stabilizes. Li 2020 (JAMA, 1482 pairs)i: objectively measured prenatal EMF → ADHD risk.En savoir plus
Melatonin bridge — EMF → pineal gland → melatonin ↓ links the sleep cascade (1) to the fertility cascade (6): cascades are in SERIES, not parallel. Five pathways: (1) HPG axis: melatonin → hypothalamus → GnRH → LH/FSH → gonads; (2) antioxidant: follicular fluid melatonin → ROS neutralization → oocyte protection (Tamura 2012 i); (3) anti-inflammatory: NF-κB ↓; (4) mitochondrial: AMPK/SIRT1 ↑; (5) epigenetic: Gdf9/Bmp15 regulation. WARNING: melatonin's HPG effect is BIDIRECTIONAL — at high concentrations it can suppress GnRH.En savoir plus
CatSper navigation disruption — EMF triggers premature CatSper activation in the epididymis. Ca²⁺ influx → hyperactivation before ejaculation → ATP/glycogen stores depleted → sperm becomes immotile in the female tract. Additionally, CatSper-dependent rheotaxis, chemotaxis, and acrosome reaction are compromised.En savoir plus
Mitochondrial Ca2+->ROS Converter — Ca2+ enters mitochondria via the mitochondrial calcium uniporter (MCU). In healthy mitochondria, this drives ATP production. In aged or damaged mitochondria, excess Ca2+ overwhelms the electron transport chain, producing superoxide radicals. The amplification factor increases with age: mitochondria over 20 years old produce progressively more ROS per unit Ca2+ influx.
Autonomic HRV — The sinoatrial (SA) node relies on T-type Cav3.1 channels for diastolic depolarization pacemaking. EMF perturbation of these channels alters heart rate variability (HRV), specifically reducing the high-frequency (HF) component that reflects vagal tone. HRV is a sensitive, non-invasive early biomarker of chronic EMF exposure — detectable before clinical symptoms emerge.
Northern Package — Iris pigmentation, optical transmission, lactase persistence and nutrition are distinct modifiers. Measure retinal light exposure rather than assuming a universal 100-fold multiplier. Co-selection and population-history interpretations require explicit inherited-trait and selection operators.En savoir plus
Bioelectric membrane potential → Ca2+/AMPK/mTOR state — Imported membrane-potential, calcium, AMPK and mTOR biology forms a conditional gate for reserve activation, growth and repair. The conditional L2 response requires an independently identified membrane kernel and calibration.En savoir plus
Receptor chemical-state memory and recovery — Receiver chemical state integrates pulses with a recovery time. Equal average input can leave different state histories when pulse spacing and recovery differ; example coefficients are structural only.En savoir plus
Tissue-specific circadian phase relationships and electrical timing — Tissue clocks interact through phase differences, not a universal scalar coherence score. Electrical timing, calcium and receiver memory enter tissue-specific phase relationships.En savoir plus
Transferable membrane machinery — Pulsed magnetic field, 1.5 mT, brief exposure of a cell-free vesicle preparation at controlled temperature. Donor myoblasts with normal TRPC1 expression versus donors in which TRPC1 was silenced; recipient cells silenced for TRPC1. TRPC1 in the vesicle membrane, together with the lipid environment and complex partners that travel with it. A calcium signal in vesicles from normal cells; no corresponding response in vesicles from TRPC1-silenced cells. Vesicles applied to recipient cells partly restored field-associated respiratory and growth responses. Restoration was measured over the recipient culture interval; persistence beyond it was not part of the design. TRPC1 silencing in the donor removed the response; supplying donor vesicles restored it. The acute local response did not require an intact source cell. Natural transfer inside tissue is a separate hypothesis.En savoir plus
Calcium as a compartment cycle — 50 Hz magnetic field at 1 mT applied to hippocampal neurons. Resting potential, ER calcium load and the release and recovery rates of the store before exposure. Plasma-membrane currents read together with the ER release and reuptake machinery: RyR and SERCA. Reduced inward and transient outward membrane currents. Membrane channels to cytosolic calcium to the ER store to mitochondria; the current change follows completed release and reuptake cycles. The store load left after exposure sets the response to the next exposure, so the change carries into the following interval. Interfering with RyR-mediated release or SERCA-mediated reuptake prevented the reported current changes. A current change is therefore also readable as a consequence of intracellular regulation, not only of direct channel action.En savoir plus
Adaptation and repair memory — Radiofrequency pre-exposure followed by a separate chemical challenge; exposure duration varied between arms. Repair capacity and damage load before the challenge, measured separately from the receptor state. The autophagy machinery as the responding system: ATG5 and ATG7 dependent flux. Increased tolerance of the later chemical challenge, read as reduced oxidative DNA damage. Autophagic flux rather than a change in the receptor: the protection appears in the handling of the load. Protection against the later challenge was still present about 20 hours after the pre-exposure ended. Pharmacological inhibition of autophagy and removal of ATG5 or ATG7 function abolished the protective response. A reduced increment can therefore be strengthened repair rather than a weakened receptor.En savoir plus
Flavin state and light history — Pulsed magnetic field with field direction varied, on cells whose light history was controlled; separately, defined illumination of purified human CRY1. CRY protein amount, flavin binding occupancy and redox state, and the preceding light history. CRY2 with the RFK/FAD system in muscle cells; human CRY1 protein with its bound flavin. Field response varied with CRY2 amount, FAD availability, field direction and light history; in the purified protein a conformational change accompanied the transition from the neutral radical to the fully reduced flavin. The transition required the sequential absorption of two photons, so the order of wavelengths and the delay between them enter the input. The intermediate state decays during the delay, so the same total dose leaves a different molecular state when the order changes. Silencing RFK and removing FAD availability changed the field response; dark growth had the same effect. The photochemical conformational change is observed, and its magnetic modulation is the next separate test.En savoir plus
One coefficient per cryptochrome, not one for all — Structural and spectroscopic characterisation rather than a field exposure. Purified protein with defined flavin occupancy. European robin CRY1 with its flavin binding site. The structure constrained physiological flavin binding and supported a clock-protein function. Applies to the interpretation of every CRY-based response: the binding site is a property of the individual protein. Not a time-dependent record; it constrains the parameters other records may use. The result bounds which subtype a parameter set may be applied to. The modulome refuses an unregistered subtype rather than substituting another protein's coefficient.En savoir plus
Direction as a separate endpoint — Direct-current electric field of 200 mV/mm in the gene screen; comparable local fields in the wound-healing experiments. Cell polarity, spatial PIP3 distribution and intrinsic motility before the field. KCNJ15/Kir4.2 acting together with polyamines; PI3Kgamma and PTEN as the polarity arm. Orientation of migration along the field axis. Ion transport to polarity signalling to directed movement of the whole cell. Directional accuracy follows the field while it is present; persistence after removal was not the endpoint. Silencing KCNJ15 removed field orientation while basic motility was retained; changing polyamine level or binding changed the response; PI3Kgamma and PTEN interventions changed electrically guided movement. Which BERM exposures reach a comparable local field magnitude is a separate calculation.En savoir plus
A message carried by the medium — Radiofrequency exposure of donor cells; recipient cells were not exposed. Cell density, medium composition and the readiness of the recipient population. The recipient cell population and its own state; the donor receptor is upstream of the transferred signal. Culture medium from exposed cells produced a protective effect in unexposed recipients. Secreted mediators in the shared medium, so the local tissue environment is part of the route. The transferred effect was present at the measured recipient time point after the donor exposure had ended. The recipients were never exposed, so the effect is bounded to a transferred signal rather than to direct field action. Together with the vesicle result this makes both the machinery and the later message transferable.En savoir plus
An immune signal reported with its function — Brief pulsed electromagnetic exposure of macrophages, with co-culture conditions defined. Macrophage activation state and the state of the co-cultured target cells. TRPC1 upstream of the STING and NF-kB route. Changed macrophage signalling through the TRPC1-STING-NF-kB route. From the immune cell to the co-cultured target cell, so the response is a tissue interaction rather than a single-cell readout. The functional change was measured after a brief exposure, so the response outlasts the exposure itself. Silencing or blocking TRPC1 abolished the reported responses. In this line of work the responses were often functionally useful, which is why a rise in an inflammatory or calcium signal always needs an endpoint beside it.En savoir plus
Measured genotype-by-exposure interaction — Controlled radiofrequency exposure during sleep in a randomised human study. Genotyped participants with their own baseline sleep electroencephalogram. CACNA1C genotype as the declared receptor-side variable. Change in the sleep electroencephalogram at the named spindle endpoint. Channel-level variation to a measurable neurophysiological readout in the same individuals. Read within the exposure night; persistence across nights was not the endpoint. The genotype was measured in the same people as the exposure and the endpoint, so the interaction is observed rather than assembled from separate populations. This is the form of genetic evidence the modulome prioritises.En savoir plus
Iris pigmentation as measured optical exposure — Identical illumination of two small groups, with the retinal light dose itself not measured. Pigmentation and ethnic background varied together between the two groups. The non-visual light input pathway; iris pigmentation acts at the entry point of the chain. Melatonin suppression of 88.9 per cent versus 73.4 per cent under the same exposure. Optical transmission to the retina, then the circadian route already carried by layer 10. Single-session measurement; no persistence claim follows from it. The measurement bounds the claim to melatonin suppression under the stated exposure. It does not measure a hundredfold retinal light dose, so the modulome replaces that coefficient with measured optical exposure.En savoir plus
Bound-ion IPR candidate — A declared bound-ion and relaxation model maps background field, frequency and ion charge/mass to phase modulation and a Bessel sideband response. The response readout and tissue transfer remain separate open assumptions.En savoir plus
Calcium compartment cycle — Plasma-membrane flux, cytosolic calcium, RyR/SERCA-dependent ER stores and mitochondria form a time-dependent cycle. Initial calcium, store change and later membrane-current changes are separately predicted; the latter can be downstream regulation.En savoir plus
Polarity and directional error — KCNJ15/Kir4.2 with polyamines and PI3Kγ/PTEN links a declared local electric field to cell orientation. Directedness, movement speed and survival are independent endpoints: a motile living cell can be misdirected.En savoir plus
TRPC1–STING immune function — The imported TRPC1–STING–NF-κB route connects a specified pulsed-field experiment to macrophage function and phagocytosis in co-culture. Calcium or inflammatory signalling alone is not an immune outcome.En savoir plus
Feedback gain and recovery — A time-indexed barrier–hormone loop compares mutual gain b·d with recovery rx·ry. Approaching equality slows recovery; positive feedback alone does not imply irreversible damage.En savoir plus
Barrier and chemical co-exposures — Barrier integrity and ion-channel state can modify delivery or response to circulating endocrine disruptors, metals and other compounds. The current BBB multiplier is a legacy diagnostic; chemical identity, tissue dose and intervention evidence must remain explicit.En savoir plus
CaMKII integration and feedback — Calcium timing and CaMKII regulation connect channel activity to neurotransmission, channel sensitivity, β-cell identity and thermogenesis in the proposed synthesis. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
GABA switch and excitation–inhibition — KCC2/NKCC1 chloride balance, inflammation and developmental timing set GABA’s functional sign and network damping; the environmental chain is a hypothesis. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Pineal mineralisation and capacity — The site proposes a calcium/redox–mineralisation branch that can reduce melatonin capacity on a slower timescale than acute circadian effects. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Mast cells, NFAT and inflammatory state — Calcium-dependent mast-cell secretion, calcineurin–NFAT regulation, cortisol-related immune balance and barrier-derived signals form distinct converging immune routes. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Methylation, histones and microRNA — DNA methylation, histone regulation and microRNA processing are separate candidate memory routes with dose- and tissue-specific direction. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Telomeres, SIRT1 and senescence — The proposed ageing branch connects redox damage, melatonin-dependent protective functions, telomere maintenance and inflammatory senescent-cell signalling. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Non-ionotropic channel signalling — Channel conformation can couple to intracellular signalling without requiring transmembrane ion flux; this imported component is distinct from calcium influx. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Hypothalamic vesicles and hormone pulses — A reported hypothalamic vesicle/protein response is the site’s candidate proximal branch into GnRH, CRH and TRH secretion; the downstream axes require distinct transfer functions. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus
Cry4a and opsin binding partners — Cry4a binds the transducin alpha subunit in the Görtemaker study. Yee measures LWO-opsin-loop binding to the same partner, providing a possible competition branch. Chemical/redox state could change occupancy through state-dependent affinities. Each binding claim retains its own experiment; the composed signalling sequence is conditional.En savoir plus
Steroidogenic supply and reserve — CaMKI–NUR77–StAR and RORα–BMAL1 converge on mitochondrial cholesterol transport. Redox reserve, autophagic cholesterol supply and mitochondrial capacity condition steroid output. Field experiments and component perturbations are displayed separately; the joined chain is BERM synthesis. Preserved hormone output can coexist with measured reserve depletion before an additional challenge.En savoir plus
MT2: evoked calcium and sodium-current brake — Melatonin reduced the field-associated sodium-current increase while enhancing depolarization-evoked calcium, without increasing resting calcium. MT2 pharmacology and store-release intervention bounded the route. MT2-dependent store release can strengthen a calcium-mediated brake on the sodium-current response.En savoir plus
Local L-channel calcium and ERK — In MIN6 cells, Bay K8644 activated ERK without a detectable bulk-Ca rise. BAPTA blocked this signal more than EGTA. GLP-1 ERK at 5 min was partly EGTA-sensitive; the 30 min response was not. A channel microdomain and the cell-average calcium signal feed distinct time-dependent ERK components.En savoir plus
L/T-channel and CaV3.2 selectivity — T-type blockers suppressed Thomas-field calcium and growth effects; L-type blockers did not. Bay K8644 gave a similar but shorter Ca peak without the same growth inhibition. In a separate AM-RF HCC protocol, CACNA1H knockdown removed the growth effect. Channel-specific calcium entry and its time course jointly determine a measured growth response.En savoir plus
AA/LTE4-mediated T-channel inhibition — A 50 Hz exposure inhibited T-type channels with increased AA/LTE4. Interventions preventing mediator increases removed inhibition, and added LTE4 reproduced it. AA/LTE4 production can mediate a reduction in a named T-type channel current.En savoir plus
Slow channel-density change — Grassi found increased whole-cell Ba current and membrane channel protein after 24–72 h, without changed single L/N-channel gating. In Bertagna 2022, thapsigargin pretreatment raised baseline fluorescence and removed the field–sham increment. Slow channel-population changes and altered calcium-store filling are separate forms of state history.En savoir plus
SERCA pretreatment and releasable stores — Grassi found increased whole-cell Ba current and membrane channel protein after 24–72 h, without changed single L/N-channel gating. In Bertagna 2022, thapsigargin pretreatment raised baseline fluorescence and removed the field–sham increment. Slow channel-population changes and altered calcium-store filling are separate forms of state history.En savoir plus
CRY amount and FAD-pocket occupancy — KL001 stabilized CRY and lengthened circadian period while reducing reporter amplitude. Biochemical competition and a CRY2 structure located binding at the FAD pocket. Protein abundance and occupied/reactive receptor fractions are independent factors in the conditional receiver capacity.En savoir plus
CoQ10: unresolved site of protection — CoQ10 attenuated some hormonal, oxidative and testicular tissue changes in a 28-rat, four-group study using GSM-modulated 3.5 GHz. Early calcium responses and repair kinetics were not separated. A reduced final impairment can arise from altered initial transmission, mitochondrial/redox production or repair; these are separate model hypotheses.En savoir plus

Organs & coordination (58)

Pituitary EMF Hub — The pituitary gland sits outside the blood-brain barrier, making it directly exposed to circulating EMF-perturbed signals. All pituitary hormone cell types (gonadotrophs, thyrotrophs, corticotrophs, somatotrophs, lactotrophs) express T-type Cav3 channels. EMF-induced Cav3 perturbation affects FSH/LH (gonadotrophs), TSH (thyrotrophs), and ACTH (corticotrophs) simultaneously.
Spermatogenesis ↓ — Redox, germ-cell and Leydig-cell states are distinct contributors to reproductive function. Bektas 2026 used GSM-modulated 3.5 GHz in 28 male rats: CoQ10 partially attenuated hormonal, oxidative and testicular histological changes. The study did not establish a 5G NR response, early calcium mediation, restored functional fertility or a repair time constant.En savoir plus
Ovulation / oocyte quality ↓ — Oocyte meiotic spindle is disrupted, granulosa cell apoptosis increases.En savoir plus
Testosterone ↓ — Leydig cell steroidogenesis disruption: StAR protein expression decreases → testosterone synthesis declines.En savoir plus
Melatonin/redox circadian mediator state — Melatonin/redox and circadian state is an intermediate shared by hormone timing, sperm function, oocyte quality, ovulation and implantation. Its direction and magnitude depend on baseline and protocol; the whole environmental pathway remains conditional.En savoir plus
NK cells ↓ (−70%) — Natural killer cells decline. Melatonin normally stimulates NK cell activity.En savoir plus
Insulin sensitivity ↓ — Melatonin deficiency disrupts pancreatic β-cell rhythm → insulin resistance.En savoir plus
Cortisol ↑ (chronic) — HPA axis hyperactivation: circadian disruption + vagal tone decrease → chronic cortisol.En savoir plus
BBB permeability ↑ — Blood-brain barrier permeability increases via eNOS activation → occludin downregulation → TJ protein degradation (Salford 2003 i; Ulusoy et al. 2025 i). The same tight junction proteins (occludin, ZO-1, claudins) are shared with the BTB. Progressive: 30 min non-damaging → 360 min structural damage. Gao et al. 2024: EMP-induced BBB disruption via tight junction protein degradation (occludin, claudin, ZO-1) — mechanistic support, though EMP differs parametrically from chronic RF.En savoir plus
BTB disruption ↑ — Blood-testis barrier disruption via Spock3-MMP2 axis at 2605 MHz (4G). Same TJ proteins as BBB. Progressive time-dependent toxicity with positive feedback: barrier damage → higher effective field → more damage. Direct spermatogenic microenvironment compromise (Yu et al. 2019 i).En savoir plus
Gut epithelium ↓ — Gut epithelial cells' rapid division cycle (3-5 days) makes them vulnerable to IF field mitotic disruption.En savoir plus
Vagal tone ↓ — Vagus nerve anti-inflammatory reflex weakening → chronic low-grade inflammation.En savoir plus
Developmental bioelectric/epigenetic reproductive-memory state — Developmental bioelectric and epigenetic states can retain earlier perturbations in organ reserves across life stages. Persistence and reversibility require separate measurements.En savoir plus
Circadian/HPA → HPG and steroidogenic gate — Circadian, stress-axis, microbiome and barrier states enter an explicit HPA–HPG gate controlling steroidogenic and reproductive timing support.En savoir plus
Hormone signal, target readiness and phase-dependent response — Effective hormone response is the time-integrated product of hormone signal and target readiness. Phase mismatch can change that integral while mean hormone concentration remains equal.En savoir plus
Microbiome/L. reuteri–oxytocin mediator state — Microbial, vagal and oxytocin intermediates provide a conditional gut–brain–HPG route. Component findings do not establish environmental EMF as its initiating cause.En savoir plus
Blood-placenta barrier state — Placental barrier and inflammatory/redox state enter implantation and pregnancy support. Conception and live birth are distinct endpoints.En savoir plus
Blood-retinal barrier state — The blood-retinal barrier is a parallel organ endpoint of calcium, redox and tight-junction regulation, without an assumed direct contribution to TFR.En savoir plus
Sertoli/germline persistent reserve — Sertoli and germline reserve represents persistent capacity separately from reversible sperm function. Barrier and developmental states contribute through separately calibrated gates.En savoir plus
Leydig/HPG androgen production support — Leydig-cell steroidogenic support combines HPG, local calcium/redox, clock, cholesterol-supply, microbiome and target-readiness states before sperm output. Measured glutathione reserve and current hormone production are distinct; their directions retain stimulus, challenge and research-family context.En savoir plus
Primordial follicle and ovarian reserve — Primordial follicle reserve and activation are persistent stock variables, separate from current ovulation. AMH/AFC observations constrain this state without proving an upstream cause.En savoir plus
Oocyte mitochondrial/redox quality — Oocyte mitochondrial and redox quality depends on reserve and physiological state; calcium and ROS have functional windows, not a universal more-is-worse rule.En savoir plus
Ovulation and steroidogenic timing gate — Ovarian reserve, oocyte quality, HPG and tissue-phase alignment jointly constrain the ovulation and steroidogenic timing gate.En savoir plus
Luteal, implantation and conception-to-live-birth support — Luteal function, embryo–endometrium timing, placental support and conception-to-live-birth survival are separate conditional reproductive gates.En savoir plus
SHBG/albumin binding and free or intratesticular androgen availability — SHBG and albumin binding separate total hormone concentration from free and intratesticular androgen availability. Matched concentrations and binding constants constrain availability; they do not by themselves determine receptor or post-receptor function.En savoir plus
AR/ZIP9 occupancy and post-receptor androgen-use capacity — Available androgen, AR/ZIP9 occupancy and post-receptor state jointly constrain effective androgen-use capacity. Tissue-specific transfer, lag and functional outcomes require calibration; equal serum testosterone does not imply equal response.En savoir plus
Pituitary (Gonadotroph) — Gonadotroph → FSH/LH: GnRH pulse decoding → FSH and LH secretion. BERM candidate after the conditional L2 operator: pituitary location and gonadotroph T-type channels may motivate an HPG-axis test; the tissue kernel is uncalibrated and does not establish an independent EMF→TFR route.En savoir plus
Adrenal Cortex (Zona glomerulosa) — Glomerulosa cell → Aldosterone: Aldosterone synthesis → sodium retention → blood pressure. BERM candidate after the conditional L2 operator: Cav3.2 and adrenal location motivate an endpoint-specific aldosterone test; the tissue kernel is uncalibrated and no chronic EMF→hypertension mapping is derived here.En savoir plus
Pancreas (β-cell) — β-cell → Insulin: Glucose-stimulated insulin secretion via VGCC → Ca²⁺. BERM candidate after the conditional L2 operator: glucose state may moderate a separately calibrated beta-cell response. The proposed interaction is not supplied by χ_geo and requires a tissue kernel.En savoir plus
Hippocampus (Dentate Gyrus) — Granule cells, neuronal progenitors: Neurogenesis, memory consolidation, learning. BERM candidate after the conditional L2 operator: Cav3.2, BBB and amyloid endpoints can be tested jointly, but their tissue response, convergence and any age interaction require independent calibration.En savoir plus
Heart (SA Node + Ventricles) — Pacemaker cells, cardiomyocytes: Heart rate, rhythm, contractile force. BERM candidate after the conditional L2 operator: SA-node and ventricular channel biology motivate HRV and contractility endpoints; an endpoint-specific tissue response is not calibrated here.En savoir plus
Thyroid (via Pituitary Thyrotroph) — Thyrotroph → TSH → Thyrocyte: Thyroid hormone synthesis (T3, T4). BERM candidate after the conditional L2 operator: pituitary and thyroid endpoints can be paired with calibrated local exposure measurements; the tissue kernel remains open and anatomy alone does not establish an effect.En savoir plus
Medium-borne bystander signals — Exposed donor cells can alter unexposed recipients through secreted mediators in shared medium. Message transfer is distinct from transfer of the membrane receptor itself, and the named recipient function determines whether a change helps or harms.En savoir plus
Reversible and persistent organ memory — Organ states carry separate reversible and persistent components with named recovery times, increments and endpoint maps. A permanent component must be explicitly declared; no field-to-organ decrement is built in.En savoir plus
Sequential fertilization gates — Capacitation, chemotaxis, acrosome reaction, zona binding, membrane fusion and pronucleus formation form successive conditional gates. Their product is a diagnostic stage model; environmental coefficients and uniform CatSper control of every stage remain assumptions.En savoir plus
mTOR, autophagy and ageing — The diagnostic extension maps declared Ca/AMPK/mTOR state to autophagy, senescence, inflammation and reproductive ageing. Drug, fasting and recovery comparisons use scenario coefficients and do not establish an environmental field effect or treatment benefit.En savoir plus
Macrophage function — TRPC1, STING and NF-κB signaling must be read with macrophage phagocytosis and tissue function. A macrophage response is not an NK-cell response and does not establish an environmental cancer risk coefficient.En savoir plus
Dopamine, motivation and reward — CaMKII, VTA calcium channels, inflammation and androgen response can feed dopamine-related motivation and reward pathways. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Serotonin and gut–brain signalling — CaMKII–TPH2 regulation and gut-dependent tryptophan availability link to central serotonin, while gut serotonin is a distinct pool. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Oxytocin and vasopressin signalling — Vagal/microbiome inputs, calcium-dependent release and receptor state connect endocrine physiology to attachment and social interaction. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Hippocampus, BDNF and plasticity — Calcium/redox state, cortisol, androgen support and BDNF participate in neurogenesis, memory and the hippocampal feedback to the stress axis. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Amygdala and threat processing — The site separates amygdala stress-related structural persistence from hippocampal responses, creating a candidate anxiety feedback route. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Thyroid and local T3 conversion — Pituitary TSH regulation and tissue Dio2/Dio3-dependent T4/T3 metabolism remain separate endocrine routes. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Adrenal aldosterone and vascular state — Adrenal Cav3.2-dependent aldosterone regulation joins salt balance and blood-pressure control separately from the cortisol arm. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Hypothalamic appetite regulation — ARC glial calcium signalling, AgRP/NPY neurons and metabolic sensing form a proposed feeding route. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Brown fat and thermogenesis — UCP1-dependent thermogenesis and SERCA/RyR calcium cycling provide two distinct routes into energy expenditure and metabolic state. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Cochlear calcium and auditory synapses — Cav1.3-mediated hair-cell transmission and inflammatory context form the site’s hearing/tinnitus pathway. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
DRG nociception and sensitisation — Cav3.2 and α2δ-related sensitisation link to pain signalling, with sex- and state-dependent response hypotheses. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Retinal dopamine and ocular growth — The site proposes convergence of retinal dopamine, circadian timing and barrier function on ocular-growth and vision endpoints. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Fetal steroid programming — Fetal Leydig Cav3–StAR steroidogenesis during a declared gestational window is a proposed input to later reproductive-development distributions. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Developmental aromatase and local steroids — The proposed CYP19/aromatase branch changes local androgen–estrogen conversion during neural development; species-specific biology must be retained. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Development of OT/AVP networks — Developmental and pubertal calcium-dependent neuropeptide/receptor organisation supplies a candidate later social-cognition route. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
PFC maturation and myelination — Channel-dependent synaptic pruning, OPC differentiation and myelination are distinct mechanisms in the proposed executive-function pathway. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Pubertal timing — Circadian/melatonin state and hypothalamic–pituitary signalling form the proposed timing gate for puberty and subsequent reproductive windows. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Interoception and body representation — Insular-circuit development is treated as a separate hypothesis about internal-body-state processing, rather than a deterministic identity outcome. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Uterine and placental pregnancy gates — Progesterone/estrogen-dependent uterine excitability, vascular calcium and placental redox state distinguish delivery timing and pregnancy vascular complications. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Maternal–infant timing and lactation — Maternal milk-borne circadian signals, skin contact and infant calcium-regulatory maturation are proposed links across the postnatal reproductive arc. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Bone, wound healing and regeneration — Controlled stimulation, bioelectric patterning and calcium responses can support healing or regeneration in specific protocols; chronic-environment and osteoporosis extrapolations are separate claims. A proposed response modifier, not a Lindgren-derived coefficient, medical recommendation or universal protective effect. Direction and magnitude require a named exposure, baseline state and endpoint.En savoir plus

Health outcomes (18)

1. Sleep disorders — Melatonin deficiency + circadian disruption → sleep disorders. The first clinical symptom.En savoir plus
2. Depression — Chronic sleep disorder + cortisol + testosterone decline → depression.En savoir plus
3. ADHD / ASD — Prenatal EMF exposure disrupts neuronal migration and synaptogenesis.En savoir plus
4. Metabolic syndrome — Insulin resistance + chronic cortisol → metabolic syndrome. Klimentidis et al. 2011 i (Proc R Soc B): 24 populations of 8 species show parallel weight gain, including laboratory animals on controlled diets (p < 10⁻⁷).En savoir plus
5. Autoimmune diseases — Vagal tone decline + chronic inflammation + gut permeability → autoimmunity.En savoir plus
6. Infertility — Cumulative: sperm quality + ovulation + testosterone + hormonal disruption → infertility.En savoir plus
7. Young-onset cancer — NK cell decline + ROS damage + mitotic disruption + immunosuppression → cancer risk.En savoir plus
Developmental trait distributions — The site’s variance hypothesis concerns the distribution of separately measured developmental traits; it requires age-window-specific tests such as its proposed AGD protocol. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Intergenerational biological memory — Parental germline marks and maternal hormonal programming are candidate transmission routes; persistence into genuinely unexposed generations is a separate untested EMF claim. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
ASD and developmental phenotypes — The website combines excitation–inhibition, synaptogenesis and inflammatory mechanisms into a testable neurodevelopmental synthesis. A developmental BERM hypothesis. Each age window, local hormone/receptor state and functional endpoint must be measured separately. Genetic or drug effects are component evidence, not proof of environmental EMF causation or an individual identity prediction.En savoir plus
Seizure, migraine and brainstem hypotheses — Network damping, spreading depolarisation and developmental calcium clearance are proposed to distinguish seizure, migraine, SUDEP and infant-vulnerability endpoints. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Neurodegeneration: four cell types — The site separates hippocampal/Alzheimer, OPC/myelin/MS, nigral dopamine/Parkinson and low-buffering motor-neuron/ALS mechanisms. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Chronic pain — Central and peripheral sensitisation are connected to sleep, stress and inflammatory feedback in the proposed chronic-pain route. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Rhythm and blood-pressure outcomes — The proposed cardiovascular branch distinguishes pacemaking/HRV, Cav1.2 repolarisation, adrenal aldosterone and vascular calcium effects. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Hearing and tinnitus — Auditory-synapse and excitability endpoints are distinct from the atlas’s general sleep and neurodevelopment categories. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Vision and myopia hypotheses — Ocular growth, retinal function and barrier state require their own endpoint-specific calibration. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
Allergic sensitisation — The proposed allergy branch combines mast-cell calcium, endocrine context and gut/barrier inflammatory inputs. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus
PCOS and endocrine convergence — Insulin, theca-cell androgen output, granulosa-cell steroid conversion and pituitary LH/FSH timing form the site’s four-organ PCOS hypothesis. Imported biological components and a conditional BERM synthesis. The L2 operator form is conditional on added matter-coupling and response premises; its gauge, scale, tissue kernel and full environmental calibration remain open. A component result does not establish population causation.En savoir plus

Reproduction & population (9)

Male × female × conception/live-birth capacity — Couple fecundability combines male sperm capacity, female ovulatory capacity and conception/live-birth support through explicit conditional gates and partner distributions. It is distinct from demand, opportunity, birth timing and cultural productive capacity. Multiplication requires stated conditional dependence; shared bottlenecks are not counted twice.En savoir plus
Reproductive motivation ↓ — Testosterone and oxytocin decline + depression + sleep disorders → approach behavior and libido decrease.En savoir plus
Age-specific fertility rate — Age-specific fertility combines couple capacity with demand/opportunity, tempo and ART/live-birth delivery. The heterogeneous waiting-time operator is an alternative aggregation, not an extra multiplier. Observed age-specific rates anchor calibration; no field-calibrated forecast is implied.En savoir plus
Total fertility rate = 5 × sum(ASFR) / 1000 — For five-year age bands and ASFR expressed per 1,000 women: TFR = 5 × Σ ASFR / 1,000. This demographic aggregation does not identify an upstream cause. Period fertility, cohort completed fertility and population size are distinct quantities.En savoir plus
Reproductively exposed encounters and attempts — Realised reproductive encounters combine state-conditioned behaviour with opportunity and the other person's response. Planned attempts and encounters without a pregnancy intention both remain possible. Success is conditioned on the actual encounter and physiological capacity; desire, action, conception and live birth are distinct measurements.En savoir plus
Childbearing timing / tempo state — The timing of attempts and births changes period ASFR/TFR separately from lifetime capacity. Cohort history and age distributions are required.En savoir plus
ART and conception-to-live-birth delivery state — ART access, uptake, procedure-specific success and live-birth delivery enter separately from spontaneous conception; do not add overlapping births twice.En savoir plus
External and interaction-conditioned reproductive opportunities — External resources, partner availability, contraception and the other person's response constrain whether an approach becomes a reproductive encounter. Social outputs alter later opportunities through time-indexed feedback. These conditions are measured separately from motivation and physiological capacity.En savoir plus
Couple heterogeneity and waiting — Couple-specific conception probabilities generate survival curves that are mixed after calculation. A finite-window supported-first-conception ratio can replace the linear couple-capacity ASFR factor under explicit assumptions; it is not itself a calendar birth rate.En savoir plus

Behaviour & society (21)

State-conditioned individual behavioural response probability — Endocrine, circadian and neural state combine with social context and learning history in a conditional distribution of desire, approach, contact and effort. A selective change in one output can coexist with preserved or increased activity in another. Realised encounters connect this branch to reproduction; reported reasons and institutional reuse remain a separate explanatory branch.En savoir plus
Caregiving amount, recipient allocation and contact feedback — The amount and target of care are separate observables. Prolactin–kisspeptin and prolactin-sensitive parental-circuit experiments identify distinct reproductive and caregiving outputs. The synthesis connects contact with later social inputs while retaining life stage, receiving circuit and lag; it does not infer impaired fertility from a chosen care target.En savoir plus
Population mixture of state-conditioned behavioural probabilities — A population mixture aggregates state-conditioned individual response probabilities over measured state and context distributions. Its weights require data; an aggregate association cannot identify a unique individual mechanism.En savoir plus
Accessible narrative attribution of a partly latent behavioural state — A reported reason is an observable interpretation of a partly latent behavioural state. It may carry causal information, but its place in the explanation must be tested against timing, intervention and alternative causes.En savoir plus
Epistapege: upstream biological state omitted from the explanatory data model — The Epistapege hypothesis concerns loss of an upstream biological state from an explanatory data model when downstream reports stand in for unmeasured causes. It predicts an observability problem requiring independent state measurements; disagreement is not itself evidence of the mechanism.En savoir plus
Institutional reuse of downstream reports as initiating explanatory variables — Institutions can reuse explanatory models that treat downstream reports as initiating variables. The proposed persistence and feedback must be studied with external records of model adoption, measurements and outcomes.En savoir plus
Neural and behavioural state — Supplied testosterone, oxytocin, dopamine, melatonin, BDNF and cortisol states enter diagnostic maps of threat sensitivity, reward, cognition, time preference and social response. These are conditional population-strategy models, not individual diagnoses.En savoir plus
Partner signals and perception — Body, behavioural and chemical signals interact with perception and metabolic state in a multiplicative pairing scenario. This branch supplies a named route from biological state to family-formation opportunity.En savoir plus
Social strategy distributions — Reward, threat, affiliation and reproductive state enter conditional distributions of competition, cooperation, parental investment, mating timing and moral/political preferences. The formulas are declared diagnostic operators, not calibrated environmental effects.En savoir plus
Collective action and institutions — Individual state distributions aggregate through cooperation, group interaction and institutional selection. Stored rules and selection environments can preserve and amplify behavioural changes; coefficients and normative categories remain scenario assumptions.En savoir plus
Social transmission and feedback — Networks, media, dependency and institutional reinforcement carry candidate transmission and recovery feedbacks. These are time-indexed social interaction operators generated by organisms; they do not establish that a political group or identity is pathological. Reproductive regulation adds partner response, caregiving contact and peer birth timing as explicit transitions. Hormone interventions and network observations constrain different links; effects return at a later time with context-specific signs.En savoir plus
Urban and institutional feedback — Settlement, infrastructure, device use and resource/selection environments change later physical inputs and partnering opportunities. Represent the return edge at the next time step; proxy-based historical calculations remain scenario comparisons. Relationship, caregiving and cohort composition carry distinct memories, so population recovery can lag a reversible endocrine change without requiring permanent biological damage.En savoir plus
BioCap and cultural production — The civilization diagnostic combines T, OXT, DA, MEL, BDNF, cortisol, vitamin D and B2 into a named weighted BioCap index. Population × BioCap × organisational efficiency yields a conditional cultural-production index; this is distinct from couple reproductive capacity.En savoir plus
Population phases and migration — Declared BioCap thresholds and interregional contrasts generate phase and migration-pressure scenarios, with solar, latitude, urbanisation and electrification histories supplied explicitly. Historical correlations do not identify the upstream physical or biological bridge.En savoir plus
Approach, effort and reward response — Androgen signalling, dopamine and stress are inputs to a conditional distribution of approach, persistence, reward sensitivity and reproductive attempts. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus
Trust, attachment and pair formation — Encounter opportunities and attachment readiness jointly condition relationship formation, care and reproductive attempts. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus
Mate signals and reciprocal matching — The site distinguishes morphological, dynamic and sensory signals from motivation and attachment; successful matching requires reciprocal reception. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus
Learning, flexibility and skill — Neural plasticity, sleep and executive function can alter the distribution of learning, maintained skills and successful cooperative actions. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus
Threat, agency and identity formation — The site’s Pathopolites model proposes dimensions of threat sensitivity, agency, cognitive flexibility and identity formation under endocrine and neural constraints. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus
Successful encounters and cooperation — Encounter frequency × functional success × temporal overlap maps individual states into relationship, cooperation and care flows. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus
Political preferences and collective action — The Patokratia model maps distributions of stress, status motivation, trust and social attachment through aggregation rules to preferences and collective action. Conditional biological-to-network aggregation hypothesis with separate interaction coefficients and time lags. Component studies do not determine a person’s identity, political views or value, and do not validate the full EMF-to-civilization route.En savoir plus

Ecology & evolution (19)

Insects ↓ — Flying insect biomass collapse. CRY navigation disruption + increased LED attraction.En savoir plus
Birds ↓ — CRY compass disruption + insect food decline. PECBMS: long-term declining trend.En savoir plus
Bats ↓ — Lindecke et al. 2026 Science i: bats use magnetoreception for navigation. RF disrupts it.En savoir plus
Amphibians ↓ — Unexplained declines in areas without habitat destruction or disease.En savoir plus
Bees ↓ — Colony Collapse Disorder + grooming behavior impairment → loss of Varroa resistance.En savoir plus
Varroa: host–parasite response — Host–parasite outcomes combine direct mite response with bee grooming, host contact and colony state. Lack of a proposed CRY navigation pathway does not establish field resistance or zero effect in mites.En savoir plus
Ticks ← increasing? — Electrostatic charge may increase tick attachment to host. Novel and falsifiable.En savoir plus
Pollination ↓ — Insect pollinator decline threatens 75% of crops. Electrostatic pollination mechanism disruption.En savoir plus
Ecosystem Cascade — CRY/RPM operates across ALL eukaryotic trophic levels simultaneously. PLANTS: CRY2 → flowering/masting disrupted (Xu 2015, Ahmad 2020). INSECTS: CRY → navigation + immunity impaired (Ferrari 2015: 2.7× bee losses). BIRDS: magnetoreception disrupted (Rosenberg 2019: -3 billion birds). MAMMALS: CRY → melatonin → HPG (Skjærvø 2015, Randall 1990). Same mechanism, different trophic level → insect decline, bird decline, sperm decline, and TFR collapse are manifestations of ONE CRY cascade.
Species-specific field encounter, sensing, physiology and dispersal state — Species-specific sensing, navigation, attachment, host encounter, physiology and dispersal mediate the physical-state response. Record local field, habitat and species traits.En savoir plus
Species-specific relative fitness and ecological-sorting state — Differences in survival, reproduction, encounter and dispersal alter relative abundance. Ecological sorting is distinct from demonstrated heritable evolutionary change.En savoir plus
Heritable traits across generations — Heritable trait distributions change across generations only under an explicit selection and inheritance operator. Genetic or common-garden evidence is needed to distinguish inheritance from plasticity.En savoir plus
Ecological electric sensing — Floral electric cues, hair/antenna sensing and predator cues can change landing, foraging and avoidance before mortality changes. Electric sensing and electrostatic mechanical force are distinct component routes.En savoir plus
Host contact and dispersal — Electrostatic force gradients can alter tick, mite or nematode host encounters; electric fields can affect spider ballooning. Encounter and dispersal changes enter interaction networks, colonisation and gene flow through species-specific operators.En savoir plus
Magnetic compass and map — Magnetotaxis, magnetic compass orientation and magnetic maps are different organism functions. CRY/light-dependent and magnetite candidates require species-specific evidence; marine cable fields additionally interact with electroreception.En savoir plus
Plant response and interaction networks — Plant physiology, floral resources and pollinator visits can change together; trophic and host–parasite interaction rates mediate abundance and ecosystem-service outcomes. Relative ecological advantage does not imply absolute growth or field immunity.En savoir plus
Plant clocks, flowering and seed set — Plant CRY/photoperiod signalling connects defined light/magnetic protocols to growth or flowering; pollinator networks then condition seed set. Keep field class, species, life stage and experimental endpoint specific. Natural sensing or a measured laboratory response does not itself establish abundance decline, parasite immunity or evolutionary change.En savoir plus
Spider electrostatic dispersal — Electric-field-elicited ballooning is a local field-to-dispersal route; repeated dispersal differences could alter colonisation and gene flow. Keep field class, species, life stage and experimental endpoint specific. Natural sensing or a measured laboratory response does not itself establish abundance decline, parasite immunity or evolutionary change.En savoir plus
Flower mites and host transport — Flower mites supply a distinct species system combining modulated electric sensing with static transport. Keep field class, species, life stage and experimental endpoint specific. Natural sensing or a measured laboratory response does not itself establish abundance decline, parasite immunity or evolutionary change.En savoir plus